Scientists have grown rudimentary teeth out of the most unlikely of
sources, human urine. The results, published in Cell Regeneration
Journal, showed that urine could be used as a source of stem cells that
in turn could be grown into tiny tooth-like structures. The team from
China hopes the technique could be developed into a way of replacing
lost teeth. Other stem cell researchers caution that that goal faces
many challenges. Teams of researchers around the world are looking for
ways of growing new teeth to replace those lost with age and poor dental
hygiene.
Stem cells - the master cells which can grow into any
type of tissue - are a popular area of research. The group at the
Guangzhou Institutes of Biomedicine and Health
used urine as the starting point. Cells which are normally passed from the body, such as those from
the
lining of the body's waterworks, are harvested in the laboratory. These
collected cells are then coaxed into becoming stem cells. A mix of
these cells and other material from a mouse was implanted into the
animals. The researchers said that after three weeks the bundle of cells
started to resemble a tooth: "The tooth-like structure contained dental
pulp, dentin, enamel space and enamel organ." However, the "teeth" were
not as hard as natural teeth.
This piece of research is not
immediately going to lead to new options for the dentist, but the
researchers say it could lead to further studies towards "the final
dream of total regeneration of human teeth for clinical therapy".
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